Other conditions relating to the use of Gadolinium are Nephrogenic Systemic Fibrosis (NSF) and retention. Both conditions are potential longer-term side effects resulting from gadolinium breakdown and interactions within the body. NSF is a rare condition associated with the use of gadolinium is a small proportion of patients with severely reduced kidney function. As part of the checks prior to injection, an assessment of your kidney function is made and where there is a need to formally check function beforehand this will be arranged. Considerations that may require formal testing of renal function include:
• Age – patients aged 75yrs or older
• History of kidney disease
• Taking medication for high blood pressure
• History of diabetes mellitus
• Having had, or planning to have, a liver transplant
Retention has more recently been recognised as a result of repeated exposure to gadolinium where small quantities have been found in tissues (mainly bones and the brain) but with no known adverse effects. In both cases, the need for contrast is assessed to ensure that is it essential to support diagnosis of your clinical symptoms and that any benefit outweighs any potential risk of harm. The contrast media used within InHealth are considered low risk, even to those with severe kidney problems, and so further reduces any concerns for harm.